miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune Diseases
نویسندگان
چکیده
منابع مشابه
P 51: The Role of T Helper 17 in Pathogenesis of Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) which causes demyelination of the nerve fibers. The etiology of this disease is not well understood but it is believed that T helpers play a central role in MS. Numerous findings support the view that Th17 cells play an essential role in pathogenesis of MS and IL-17 secreting T (Th17) cells have a role in infla...
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Many autoimmune diseases are driven by self-reactive T helper (Th) cells. A new population of effector CD4(+) T cells characterized by the secretion of interleukin (IL)-17, referred to as Th17 cells, has been demonstrated to be phenotypically, functionally, and developmentally distinct from Th1 and Th2 cells. Because the liver is known to be an important source of transforming growth factor- β ...
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Complete List of Authors: Papp, Gábor; University of Debrecen Medical Center, Institute of Medicine, Department of Clinical Immunology Szabó, Krisztina; University of Debrecen Medical Center, Institute of Medicine, Department of Clinical Immunology Szekanecz, Zoltán; University of Debrecen Medical Center, Institute of Medicine, Department of Rheumatology Zeher, Margit; University of Debrecen Me...
متن کاملp 51: the role of t helper 17 in pathogenesis of multiple sclerosis
multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) which causes demyelination of the nerve fibers. the etiology of this disease is not well understood but it is believed that t helpers play a central role in ms. numerous findings support the view that th17 cells play an essential role in pathogenesis of ms and il-17 secreting t (th17) cells have a role in infla...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.593473